The a16z Show

Andreessen Horowitz

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What Happens When a Public Company Goes All In on AI

4/1/2026 • 27 min

David Haber speaks with Owen Jennings, executive officer and business lead at Block, about how the company rebuilt itself around AI agents, small squads, and internal tools like Goose and Builder Bot after restructuring more than 40% of its workforce. They discuss what it took to execute a major restructuring, how teams of three are now doing what teams of 14 us… Play episode

How Radiant and Heron Are Rethinking Power Generation and Delivery
Marc Andreessen on Evaluating Founders and AI's Consumer Surplus
The SpaceX and Tesla Playbook for Hard Tech Startups
Security, Resilience, and the Future of Mobile Infrastructure
Submarines and the Future of Defense Manufacturing
The Missing Power Layer of Modern Warfare
Why Every Satellite Needs Earth | Northwood CEO on a16z
Inside Palantir: Building Software That Matters with Shyam Sankar
AI Just Gave You Superpowers — Now What?
AI, Supply Chains, and the Future of Economic Power
What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
AI Startups vs. Big Chatbots — With Olivia Moore
Marc Andreessen on the Mindset of Great Founders — with David Senra
Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon
Palantir CEO Alex Karp on the Zero-Sum AI Race
What It Takes to Clear a Million Crimes a Year with Flock Safety's CEO
The Top 100 Gen AI Consumer Apps
Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity
Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next
Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power
Deploying AI in Healthcare
Ben Horowitz On What Makes a Great Founder
Chris Dixon: From Quant Trading to Building a16z Crypto
a16z's New Media Playbook
When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market
Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics
Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes Afte…
AI’s Capital Flywheel: Models, Money, and the Future of Power
From Copilots to Agents: Rebuilding the Company Around AI
WSJ x a16z: The Next 25 Years of Defense Innovation
Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company
Balaji and Dan Wang: The Engineering State vs Lawyerly State
Anish Acharya: Is SaaS Dead in a World of AI?
How Magic Johnson Built a Billion-Dollar Portfolio in 30 Years
Marc Andreessen: Who Runs the World’s AI?
The State of Markets
Balaji & Benedict Evans: When Tech Breaks Industries
Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES
Why America’s Health Crisis Is an Incentive Problem
Palmer Luckey on Hardware, Building, and the Next Frontiers of Innovation
David Solomon & Ben Horowitz on Building Organizational Resilience & Navig…
“Anyone Can Code Now” - Netlify CEO Talks AI Agents
Marc Andreessen on Why This Is the Most Important Moment in Tech History
Ben Horowitz and Balaji Srinivasan on Netscape and Network States
Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection
The Hidden Economics Powering AI
How Mintlify Is Rebuilding Documentation for Coding Agents
Inferact: Building the Infrastructure That Runs Modern AI
Martin Casado on the Demand Forces Behind AI

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