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This Week in Startups

Jason Calacanis

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3 AI Agents That Actually Replaced Human Jobs | E2272

Anthropic just pulled the plug on Claude subscriptions for OpenClaw and every third party agentic tool. So Jason and Lon welcome back three of our top TWiST OpenClaw experts to break down what it means, how much it’s going to cost now, and whether this is truly the end of the subsidized AI era. And they all brought demos! We’re checking out ClawChief from Ryan Carson, Alex Finn’s agent Henry, and Yazin Alirhayim’s Sidecast protocol, inspired by a special request from JCal! Hosts Jason Calacanis: http://x.com/jason Lon Harris: https://x.com/lons Guests Ryan Carson: https://x.com/ryancarson Clawchief: https://github.com/snarktank/clawchief Alex Finn: https://x.com/AlexFinn Creator Buddy: https://www.creatorbuddy.io/ Yazin Alirhayim: https://x.com/yazins OpenOats / Sidecast: https://github.com/yazinsai/OpenOats Further Reading The Checklist Manifesto by Atul Gawande: https://www.amazon.com/Checklist-Manifesto-How-Things-Right/dp/0312430000 Marc Andreessen on AI job loss: https://x.com/pmarca/status/2040919227641856307 OpenAI acquires TBPN: https://openai.com/index/openai-acquires-tbpn/ This Week In Startups is made possible by: Gusto - https://Gusto.com/twist Vanta - https://vanta.com/twist Shopify - https://shopify.com/twist Plaud - https://Plaud.ai/twist Today’s show: Timestamps: 0:00 Welcome back to TWiST 0:32 Jason's thinks Andor is as good as Empire Strikes Back… 2:30 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 3:26 Check out the checklist manifesto! https://www.amazon.com/Checklist-Manifesto-How-Things-Right/dp/0312430000 6:36 Our guests Ryan Carson, Alex Finn, and Yazin Alirhayim, and join the show 10:28 Gusto - Check out the online payroll and benefits experts with software built specifically for small businesses and startups. Try Gusto today and get three months FREE at https://Gusto.com/twist. 10:46 People are automating their coworkers and getting them fired… 18:32 Anthropic Bans OpenClaw 20:06 Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist 24:06 How "caveman talk" makes AI works better 27:31 Alex thinks $2000/ month subscription plans are inevitable for AI. 29:31 Why is nobody using the leaked Anthropic Model? 30:30 Shopify: Turn those What If's into sales with the ecommerce platform powering millions of businesses. Sign up for your $1-per-month trial today at https://shopify.com/twist 32:37 Open models have been 6 months behind for the past few years 35:53 Why did OpenAI acquire TBPN? 42:01 Tactical/ Practical: The product itself is the most important thing 44:31 Demo or Die! Yazin is back to show off OpenOats 55:05 Ryan's "Claw Chief" https://github.com/snarktank/clawchief/blob/main/skills/executive-assistant/SKILL.md?plain=1 1:02:14 Alex's big announcement, "Henry intelligent machines" 1:12:33 Alex Finn DESTROYS Higgsfield's marketing strategy 1:15:35 Throwback to "Pay Per Post" Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

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