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The Rise of the Full-Stack Builder and Hyper-Leveraged Generalist with Microsoft CEO…

6/4/2026 • 42 min

What does it mean for a business to truly operate at the AI frontier? In a special crossover episode at Microsoft Build, Sarah Guo and Elad Gil team up with Latent Space host “swyx” to talk with Microsoft Chairman and CEO Satya Nadella about the future of AI platforms, software development, and the tech ecosystem. Satya reflects on the latest breakthroughs from … Play episode

Building an AI Guardian for Enterprise with Onyx Security CEO Maxim Bar Ko…
The Story Behind Cerebras’ $63 Billion IPO with Founder and CEO Andrew Fel…
Pax Silica: Inside the Trump Administration’s Tech Strategy with US Under …
Amex Global Business Travel: The World’s First AI Take Private with Long L…
Baseten CEO Tuhin Srivastava on the AI Inference Crunch, Custom Models, an…
SAP: Bringing the ‘Operating System’ of a Company into the AI Era with CTO…
Scaling Global Organizations in the Age of AI with ServiceNow Chairman and…
The Agentic Economy: How AI Agents Will Transform the Financial System wit…
AI for Atoms: How Periodic Labs is Revolutionizing Materials Engineering w…
Andrej Karpathy on Code Agents, AutoResearch, and the Loopy Era of AI
From Coder to Manager: Navigating the Shift to Agentic Engineering with No…
How Capital is Powering the AI Infrastructure Buildout with Magnetar Capit…
From SaaS to AI-First: How Companies Are Reshaping Innovation
Rivian’s Roadmap to AI Architecture and Autonomy with Founder and CEO RJ S…
Introducing 4D Creation Open Beta: NPCs, 4D Worlds, and the Future of Gami…
Why Cryopreservation is No Longer Science Fiction with Until Co-founder an…
No Priors Live: Building Durable Software in the AI Age with MongoDB Presi…
AI and the Future of Warfare with US Under Secretary of War Emil Michael
NVIDIA’s Jensen Huang on Reasoning Models, Robotics, and Refuting the “AI …
The 2026 AI Forecast: Foundation Models, IPOs, and Robotics with Sarah Guo…
The Future of Voice AI: Agents, Dubbing, and Real-Time Translation with El…
Scaling Legal AI and Building Next-Generation Law Firms with Harvey Co-Fou…
Sunday Robotics: Scaling the Home Robot Revolution with Co-Founders Tony Z…
How AI Will Accelerate Breakthroughs in Biotechnology with Benchling CEO S…
Meet Snowflake Intelligence: A Personalized Enterprise Intelligence Agent …
The Best of 2025 (So Far) with Sarah Guo and Elad Gil
Reinventing the Developer Terminal with Warp Co-Founder and CEO Zach Lloyd
Unlocking the Road to Energy Abundance with Base Power CEO and Co-Founder …
Humans&: Bridging IQ and EQ in Machine Learning with Eric Zelikman
The Impact of AI, from Business Models to Cybersecurity, with Palo Alto Ne…
Reinventing K-12 Education Using AI with Alpha School Principal Joe Lieman…
AI Agents Talking to AI Agents: Reinventing Commerce with Decagon CEO Jess…
Jared Kushner: BrainCo, Affinity Partners, and the Geopolitics of AI
A New Operating System for Physicians with OpenEvidence Founder Daniel Nad…
Reshaping America’s Economy for the Superintelligence Century with Jacob H…
How Agentic AI is Transforming The Startup Landscape with Andrew Ng
Chips, Neoclouds, and the Quest for AI Dominance with SemiAnalysis Founder…
The Shifting Value of Content in the AI Age with Cloudflare CEO Matthew Pr…
America’s Plan to Dominate the Full AI Stack with Sriram Krishnan
The Power of Quality Human Data with SurgeAI Founder and CEO Edwin Chen
Asimov: Building An Omniscient RL Oracle with ReflectionAI’s Misha Laskin
Why Platforms Win and Point Solutions Fail with Rippling CEO Parker Conrad
Chai-2: The AI Model Accelerating Drug Discovery with Chai Discovery Co-Fo…
Meet AlphaEvolve: The Autonomous Agent That Discovers Algorithms Better Th…
The Operating System for Self Driving Cars (and Tanks, and Trucks...) With…
Will we have Superintelligence by 2028? With Anthropic’s Ben Mann
Teaching AI to Understand the Physical World, with Dr. Fei-Fei Li of World…
AI Consolidation, Biotech Opportunities, and World Models with Sarah and E…
AI is Making Enterprise Search Relevant, with Arvind Jain of Glean

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